DEcompressive CRAniectomy Trial (DECRA)

Multi-centre prospective randomised trial of early decompressive craniectomy in patients with severe traumatic brain injury.  In collaboration with the Alfred Department of Anaesthetics (Associate Professor Jamie Cooper), CCRE Therapeutics has established the data collection and management system for this study on decompression head injury. 

The study tests the hypothesis that early decompressive craniectomy will improve long term neurological outcome in patients with severe traumatic brain injury and intracranial hypertension which is refractory to conventional management.